4-Tolylboronic acid, also called p-tolylboronic acid or 4-methylphenylboronic acid, is an arylboronic acid used mainly as a coupling partner in organic synthesis. Its CAS number is 5720-05-8, its molecular formula is C7H9BO2, and its molecular weight is approximately 135.96 g/mol. Buyers typically evaluate it for Suzuki–Miyaura coupling, where it can provide a 4-methylphenyl group, while confirming the grade, assay, documentation, and delivery terms required for their process. At Maison Chemical, we help buyers assess product requirements and request a quotation based on intended use and order quantity.
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This guide is intended for procurement teams, research chemists, process-development groups, and manufacturers evaluating 4-Tolylboronic acid as a synthesis reagent. It provides a practical overview rather than a substitute for a product specification or reaction-development study. Buyers should use the supplier’s current documentation to confirm the details that apply to a particular lot. Requirements can differ between exploratory laboratory work and a manufacturing process.
4-Tolylboronic acid is an organoboron compound with a boronic acid group attached to a para-methyl-substituted phenyl ring. The “4-” or “para-” designation identifies the relative position of the methyl group on the aromatic ring. In synthesis, the boronic acid functionality can participate in cross-coupling reactions, including Suzuki–Miyaura coupling, when suitable reaction partners and conditions are used. Reaction performance depends on the substrate, catalyst system, solvent, base, and other experimental variables.
Common identifiers include CAS 5720-05-8, the formula C7H9BO2, and a molecular weight of about 135.96 g/mol. Product listings may use names such as 4-methylphenylboronic acid, p-tolylboronic acid, or 4-tolylboronic acid. Buyers should compare identifiers, not just names, when matching an order to a procedure or internal material record. A current specification and label should confirm the identity of the supplied material.
Reference sources and supplier listings commonly describe the material as a solid, but appearance and detailed specifications should be checked against the lot documentation. A melting-point range is sometimes reported around 256–260 °C; treat this as a reference value rather than a guaranteed release criterion unless it appears in the supplier’s specification. Buyers should also confirm the assay method and acceptance limit, impurity controls, packaging, and any stated storage recommendations. We recommend evaluating the actual documentation provided for the offered grade.
| Item | Buyer reference | What to verify |
|---|---|---|
| Product identity | 4-Tolylboronic acid; CAS 5720-05-8 | Match the name and CAS number to your approved material record. |
| Molecular formula | C7H9BO2 | Check consistency across the specification and safety documentation. |
| Molecular weight | Approximately 135.96 g/mol | Use the value appropriate to your calculation and procedure. |
| Purity and quality | Grade- and supplier-specific | Request the stated limit, analytical method, and available batch documents. |
The primary reason buyers select 4-Tolylboronic acid is its use as an aryl donor in synthesis. In a suitable cross-coupling reaction, it can be used to introduce a 4-methylphenyl group into a target molecule. This makes it relevant to research and development workflows involving substituted biaryl or related structures. The appropriate choice still depends on the desired product and the chemist’s validated reaction conditions.
Before selecting this reagent, confirm that the target structure requires the para-methyl-substituted aryl group rather than a different tolyl isomer or an unsubstituted phenyl group. Review the reaction procedure for its specified reagent form, equivalents, catalyst, base, and solvent. If the procedure has not been validated with this material or supplier grade, plan an appropriate small-scale assessment before moving to larger quantities. We do not assume that a reagent’s identity alone guarantees a particular yield or reaction outcome.
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For process development, consider how the material will be weighed, charged, and controlled through the reaction and work-up. Discuss moisture sensitivity, impurity tolerance, and any analytical requirements with your technical team using the supplier’s documentation as a starting point. If your process has defined limits for boronic acid content or specific impurities, state those requirements when requesting a quote. This helps determine whether the offered grade is suitable for evaluation.
Specify the required assay or purity range, analytical method if relevant, and any limits for impurities or residual solvents. Ask which documents are available for the product and whether batch-specific documentation can be provided for the quoted lot. If your organization requires a particular document format or review process, raise it before purchase. Do not assume that every grade includes the same testing or paperwork.
Provide the intended order quantity and the delivery destination when requesting pricing. For comparison, buyers may request quotes for quantities such as 100 g, 1 kg, or a larger production requirement; these are planning examples, not a statement of available stock or standard pack sizes. Confirm the actual pack configuration, MOQ, lead time, and shipment terms directly with the supplier. Availability and schedules can vary by lot and destination.
Compare quotations on a like-for-like basis, including grade, quantity, packaging, documentation, and delivery terms. A lower price may not represent equivalent material or service if specifications differ. Review the current safety data sheet and the supplier’s handling and storage instructions before receiving the product. Your organization’s chemical safety procedures should govern handling, storage, and disposal.
Pricing for 4-Tolylboronic acid is generally quote-dependent and may reflect grade, order volume, packaging, availability, and shipping destination. Minimum order quantity and lead time should also be confirmed for the specific offer rather than inferred from a general listing. For an accurate quotation, share the required quantity, target specification, destination, and any documentation needs. If you have a delivery deadline, state it when making the inquiry so the supplier can check feasibility.
At Maison Chemical, we support B2B inquiries by reviewing requested identity, quantity, specification, and destination details before preparing a product offer. We can discuss available product information and documentation for the quoted material, subject to confirmation for the specific lot. Buyers should provide any project-specific quality or packaging requirements at the inquiry stage. This makes it easier to assess whether the offer matches the intended procurement need.
4-Tolylboronic acid CAS 5720-05-8 is a para-methyl-substituted arylboronic acid used chiefly as a coupling reagent in organic synthesis. Its identity can be checked against the CAS number, formula C7H9BO2, and molecular weight of approximately 135.96 g/mol, but procurement suitability depends on the grade and lot-specific documentation. Before ordering, confirm the required specification, quantity, packaging, MOQ, lead time, and delivery terms. Contact Maison Chemical with these details to request a quotation and evaluate the offered material for your application.
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