If you are sourcing 3-(Hydroxymethyl)phenylboronic acid, CAS 87199-15-3, the key purchasing priorities are identity confirmation, assay and impurity control, packaging suitability, and reliable batch-to-batch supply. I identify this compound as an aromatic boronic acid intermediate containing both a boronic acid group and a hydroxymethyl group, making it relevant to synthetic chemistry and pharmaceutical intermediate development. The commonly assigned molecular formula is C7H9BO3, with a calculated molecular weight of approximately 151.96 g/mol. Before placing a bulk order, I recommend confirming the required grade, analytical specifications, documentation, quantity, and delivery schedule with the supplier.
I prepared this guide for procurement teams, process chemists, research and development groups, pharmaceutical intermediate manufacturers, and chemical distributors evaluating 3-(Hydroxymethyl)phenylboronic acid. It is especially useful when a project is moving from laboratory screening toward repeated synthesis or commercial-scale sourcing. The purpose is not to replace a supplier’s current technical package, but to help buyers ask the right questions before qualification.
This material may also support purchasing comparisons between several suppliers. A lower quoted price does not necessarily represent a lower total cost if the material requires additional purification, arrives with incomplete documents, or cannot be supplied consistently. For that reason, I recommend evaluating technical quality, supply continuity, and service together.
3-(Hydroxymethyl)phenylboronic acid is a substituted aryl boronic acid. The molecule combines an aromatic ring with a boronic acid group and a hydroxymethyl substituent, creating two chemically useful functional features in one intermediate. In practical synthesis, the boronic acid group is often considered for carbon–carbon bond-forming reactions, while the hydroxymethyl group may be retained, protected, oxidized, or converted into another derivative depending on the route.
The compound is generally handled as a specialty research or manufacturing intermediate rather than as a finished pharmaceutical ingredient. Its suitability must therefore be judged against the reaction process and the customer’s internal quality system. I advise buyers to confirm whether they require material for exploratory research, process development, registration batches, or routine commercial production because the documentation and release criteria may differ at each stage.
A principal reason to evaluate this compound is the reactivity associated with the aryl boronic acid functionality. Boronic acids are commonly used in Suzuki–Miyaura-type coupling strategies to construct substituted biaryl or aryl–heteroaryl structures. Actual reaction performance depends on the coupling partner, catalyst system, base, solvent, temperature, concentration, and sensitivity of the complete molecule, so I do not treat the compound as a guaranteed solution for every coupling route.
The hydroxymethyl substituent can provide a useful handle for additional molecular modification during medicinal chemistry or intermediate development. Chemists may investigate selective protection, oxidation, esterification, or other transformations, subject to route-specific compatibility. The value of the material is therefore often linked to how efficiently it enables a desired synthetic sequence rather than to a single fixed end use.
Aromatic boronic acids can also be considered in functional material research and molecular design studies. However, the required purity profile may be different from that used in pharmaceutical intermediate work. For example, a materials project may prioritize trace-metal control or a particular physical form, while a process chemistry project may place greater emphasis on reaction reproducibility and residual solvent limits.
A suitable specification should begin with unambiguous identity. I recommend checking the product name, CAS number, molecular formula, molecular weight, appearance, and analytical identity data. Depending on the supplier’s quality system, supporting data may include NMR, infrared spectroscopy, liquid chromatography, mass spectrometry, or other appropriate methods.
| Specification Area | What to Confirm | Why It Matters |
|---|---|---|
| Identity | CAS 87199-15-3, structure, formula, and analytical identification | Confirms that the supplied material matches the requested intermediate |
| Assay and related substances | Assay method, reporting basis, and impurity profile | Helps assess reaction input quality and purification requirements |
| Water content | Test method and acceptance limit, reported in % or an agreed unit | Boronic acids can be sensitive to handling and moisture conditions |
| Residual solvents | Solvent names, limits, and analytical method | Supports process safety, reproducibility, and downstream compliance |
| Packaging | Container type, size, sealing, labeling, and storage guidance | Protects the material during storage and international transportation |
Three basic data points are useful when screening purchasing documents: CAS number 87199-15-3, molecular weight approximately 151.96 g/mol, and a typical commercial evaluation quantity that may begin at 1 kg for development discussions. The quantity is not a universal MOQ, and I recommend treating it only as a planning example rather than a guaranteed offer. Actual assay, water, impurity, and packaging limits must come from the supplier’s current specification and certificate of analysis.
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First, I ask whether the material is intended for reaction screening, process development, scale-up, or routine production. Early-stage research may accept a broader specification if the chemist can characterize the material internally. Commercial or regulated work usually requires more formal documentation, traceability, change-control communication, and a specification aligned with the customer’s quality system.
Next, identify the attributes that can affect the reaction or downstream intermediate. These may include assay, individual impurities, total impurities, water, residual solvents, inorganic residues, and trace metals. A buyer should avoid requesting limits that are unrelated to the process, but should also avoid accepting a generic specification without understanding its analytical basis.
Before approval, request the available specification sheet, representative certificate of analysis, safety data sheet, packaging information, storage recommendations, and manufacturing or lot information that the supplier is able to provide. If the material will enter a regulated supply chain, discuss whether additional quality documents or audit support are required. I recommend comparing documents from more than one lot whenever consistency is important.
Bulk supply decisions should include quantity, packaging configuration, lead time, shipping conditions, payment terms, and forecast expectations. Pricing is normally influenced by quantity, specification, packaging, production scheduling, and destination. Rather than relying on a general market estimate, I recommend requesting a project-specific quotation based on the exact grade and delivery requirement.
One common mistake is comparing suppliers only by price per kilogram. This approach can overlook differences in assay basis, impurity reporting, packaging, documentation, and available stock. A second mistake is assuming that a laboratory sample specification automatically applies to a commercial batch without a formal scale-up review.
Another risk is failing to clarify the physical form and storage conditions before shipment. Boronic acid intermediates may require controlled handling to protect quality, and the appropriate conditions should be confirmed from the supplier’s technical documentation. Buyers should also avoid approving material based on a product name alone; CAS number, structure, analytical identity, and lot-specific results should be reviewed together.
When I evaluate a supplier, I look for clear communication between sales, technical, quality, and logistics teams. The supplier should be able to explain what is included in the standard product package, what can be customized, and which requirements need advance confirmation. Consistent answers are particularly important when a customer is planning repeat orders or a multi-stage development program.
Maison Chemical supports business buyers by discussing product specifications, quantity requirements, packaging preferences, documentation needs, and shipment planning for 3-(Hydroxymethyl)phenylboronic acid CAS 87199-15-3. We can review whether the requested quality profile is suitable for laboratory, process development, or bulk procurement discussions. Availability, MOQ, lead time, and final commercial terms should be confirmed for each inquiry because they depend on the required grade and order plan.
The best way to purchase 3-(Hydroxymethyl)phenylboronic acid CAS 87199-15-3 is to match the material specification to the actual synthesis and supply stage. For most buyers, the decision should center on verified identity, suitable assay and impurity control, appropriate moisture and solvent limits, secure packaging, and dependable commercial communication. No single grade is automatically optimal for every application, so a written technical comparison is more reliable than a catalog description alone.
As a next step, prepare your target quantity, intended application, required specification, packaging preference, destination, and requested delivery window. Send these details to Maison Chemical for a focused B2B quotation and technical discussion. We can then help determine whether the requested material profile, documentation package, and supply plan are appropriate for your project.
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