If I were procuring 3,5-Difluorophenylboronic acid, CAS 156545-07-2, I would begin by confirming the chemical identity, required purity, intended reaction, packaging, and delivery destination before comparing prices. This compound is an aryl boronic acid used primarily as a building block in palladium-catalyzed cross-coupling chemistry, including Suzuki–Miyaura reactions. Its commonly reported molecular formula is C6H5BF2O2, with a calculated molecular weight of approximately 157.91 g/mol. Maison Chemical can support B2B buyers with product clarification, specification review, quotation preparation, packaging coordination, and export-oriented supply communication.
For more information, please visit our website.
This guide is intended for pharmaceutical and agrochemical research teams, medicinal chemistry laboratories, contract development and manufacturing organizations, fine chemical distributors, and purchasing departments sourcing specialty organic boronic acids. It is also useful for buyers who need to distinguish a technically suitable material from a product that is only described by a matching name. Because procurement requirements vary between laboratory evaluation and commercial synthesis, I recommend treating identity confirmation and application fit as separate decisions.
For a small research order, the most important factors may be reliable documentation, suitable packaging, and a practical minimum order quantity. For scale-up, buyers should also evaluate batch consistency, production capacity, storage conditions, lead-time planning, and transport requirements. A supplier that can answer technical and commercial questions clearly may reduce avoidable delays during project transfer.
3,5-Difluorophenylboronic acid contains an aryl boronic acid group and two fluorine substituents on the phenyl ring. The boronic acid functionality is valuable because it can participate in carbon–carbon bond-forming reactions, while the fluorine atoms can influence the electronic properties of the aromatic ring. The exact impact on reaction performance depends on the reaction partners, catalyst system, solvent, base, temperature, and work-up procedure.
CAS 156545-07-2 should be used as an important identity reference, but I would not rely on the CAS number alone. A procurement file should also compare the product name, molecular formula, molecular weight, appearance, assay specification, impurity profile, analytical data, and packaging label. If the material is intended for a regulated or tightly controlled project, the buyer should request the relevant documentation before placing a purchase order.
Commercial descriptions of this material commonly focus on purity and availability, but “purity” should be understood in the context of the supplier’s analytical method and specification. For example, an assay result may be reported by HPLC, NMR, or another method, and these methods do not provide identical information. I recommend asking the supplier to identify the test method, acceptance criterion, and whether the reported value applies to the current batch.
| Procurement item | What to confirm | Why it matters |
|---|---|---|
| Identity | CAS 156545-07-2, chemical name, formula, molecular weight | Reduces the risk of ordering an isomer or similarly named compound |
| Quality | Assay method, purity target, key impurities, batch information | Supports reaction development and reproducibility |
| Physical presentation | Appearance, net weight, container type, labeling | Helps with receiving, storage, and laboratory handling |
| Documentation | Certificate of analysis, safety data sheet, packing list, invoice | Supports internal quality review and shipment processing |
The commonly cited molecular weight of approximately 157.91 g/mol is useful for calculating reaction quantities and preparing internal purchasing specifications. However, I would still ask the supplier to confirm the value used on its current technical documents. If the project requires a specific water content, residual solvent limit, particle form, or elemental impurity profile, these requirements should be stated explicitly rather than assumed to be included in a standard product grade.
In medicinal chemistry, 3,5-Difluorophenylboronic acid may be selected to introduce a difluorinated aryl fragment into a target molecule through cross-coupling. At this stage, buyers often need relatively small quantities and fast technical feedback rather than a large production commitment. I suggest confirming whether the supplier can offer the requested package size and provide a batch-specific certificate before the first experiment.
For process development, the purchasing decision should include more than a single successful laboratory reaction. The team may need to assess batch-to-batch consistency, supply continuity, packaging suitability, and the supplier’s ability to discuss larger quantities. A material that meets a laboratory screen may require additional controls when used in a multi-step route or a larger reaction vessel.
Distributors should confirm the product’s commercial name, labeling requirements, target market, packaging configuration, and export documentation. They should also avoid publishing a purity or delivery promise that has not been confirmed for the specific batch and destination. A clear product data package makes it easier to respond accurately to downstream customer inquiries.
The first decision is whether a standard commercial grade is sufficient. If the project has a narrow reaction tolerance, the buyer may need a tighter impurity or water specification, but tighter specifications can affect price and lead time. I recommend asking the chemist, quality team, and purchasing team to agree on which requirements are essential and which are preferred.
Maison Chemical Product Page
The second decision concerns quantity and supply continuity. A one-time research order and a recurring manufacturing requirement should not be evaluated using the same sourcing model. For recurring demand, ask whether the supplier can discuss forecast planning, repeat-batch documentation, and a realistic production schedule without making assumptions about unconfirmed capacity.
The third decision is logistics. Confirm the shipping country, consignee requirements, packaging size, customs information, and any applicable dangerous-goods or chemical import procedures with the responsible logistics team. Delivery time should be treated as an estimate until the supplier confirms stock status, production timing, and destination-specific shipping conditions.
The price of 3,5-Difluorophenylboronic acid may vary with purity, order quantity, packaging, production status, and destination. I would request at least two or three quantity tiers, such as laboratory scale, intermediate scale, and larger project demand, while asking the supplier to state whether the offer is based on available stock or new production. The lowest quoted unit price is not necessarily the lowest procurement cost if it requires excess inventory or creates a long waiting period.
Minimum order quantity should be evaluated against the project’s consumption plan and storage capability. For an early-stage program, a smaller pack can limit inventory exposure, while a larger order may be more economical for a validated route. Lead time should be recorded in business days or calendar days, and the quotation should distinguish preparation time from international transit time; for example, a stated 10-business-day preparation period does not automatically represent total delivery time.
When I evaluate a supplier, I look for a consistent answer to five questions: Can the company identify the product correctly? Can it provide a batch-relevant specification? Can it explain packaging and shipment arrangements? Can it quote according to the buyer’s quantity and destination? Can it communicate clearly if availability changes?
Maison Chemical approaches this product as a B2B specialty chemical supply project rather than a simple catalog transaction. I can help buyers organize the requested specification, review quantity and packaging needs, prepare a quotation, and coordinate product documents for internal evaluation. Availability, exact pricing, batch data, and delivery timing should be confirmed for each inquiry because these details can change with order size and destination.
One common mistake is comparing products only by name and CAS number while overlooking assay method, impurity limits, or packaging. Another is requesting a delivery date without providing the quantity, destination, and required documentation. Buyers should also avoid treating a supplier’s indicative specification as a guaranteed batch result unless the supplier has confirmed it in writing for the ordered material.
A further mistake is waiting until after the purchase order to discuss storage, customs paperwork, or quality review. These topics are easier to resolve during quotation because they may influence packaging, shipping method, and lead time. I also recommend retaining the quotation, approved specification, certificate, and receiving records as one procurement file.
For 3,5-Difluorophenylboronic acid CAS 156545-07-2, the right procurement decision combines identity verification, application-specific quality requirements, practical quantity planning, and supplier responsiveness. The compound is commonly used as a fluorinated aryl building block, but suitability must be confirmed against the buyer’s actual reaction and quality requirements. The key reference data include CAS 156545-07-2, formula C6H5BF2O2, and approximate molecular weight 157.91 g/mol.
As a next step, send Maison Chemical your required quantity, target purity, packaging preference, destination, expected purchase frequency, and documentation needs. I can then help structure a product inquiry and provide a quotation subject to current availability and confirmed commercial conditions. This approach gives your technical and purchasing teams a clearer basis for approving the material and planning the next order.
Want more information on 3,5-Difluorophenylboronic acid CAS 156545-07-2? Feel free to contact us.